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Bradley Charles Lega, MD $$

Pediatric Neurosurgeon

Associate Professor at UT Southwestern Medical Center

Languages Spoken:
English
UT Southwestern Pediatric Group

Biography

Bradley Lega, M.D., is a neurosurgeon at Children’s Health and an Associate Professor at UT Southwestern Medical Center who specializes in evaluation and surgical treatment of epilepsy, brain tumors and disorders of the spine.

Dr. Lega received his medical degree from Baylor College of Medicine. He completed his neurological surgery residency at the University of Pennsylvania and performed a fellowship in epilepsy surgery at the Cleveland Clinic.

Tools like stereo EEG help me perform brain surgery more safely.
Dr. Lega

Dr. Lega is one of the few neurosurgeons in the country who uses stereoelectroencephalography, or stereo EEG, to locate the origin of epileptic seizures in the brain and determine if a patient is a candidate for surgery to treat the seizures. Less invasive than the traditional approach, stereo EEG involves electrodes placed in the brain to record electrical activity during seizures.

“Tools like stereo EEG help me perform brain surgery more safely,” he says. “As neurosurgeons, we want every bit of data possible to help us identify the part of the brain that is causing the seizures so we can do our job with confidence.”

Dr. Lega’s research focuses on how brain conditions affect memory. The research he began at the University of Pennsylvania and continues at UT Southwestern centers on preserving memory function and restoring memory to patients with brain injuries or brain tumors.

Dr. Lega is a member of the American Association of Neurological Surgeons, the Congress of Neurological Surgeons and the Society for Neuroscience.

Education and Training

Medical School
Baylor College of Medicine (2006)
Internship
University of Pennsylvania School of Medicine GME (2007), General Surgery
Residency
University of Pennsylvania Medical Center (2013), Neurosurgery
Fellowship
Cleveland Clinic Foundation (2014), Epilepsy
Board Certification
American Board of Neurological Surgery
  • Research Interests

    • Memory encoding and retrieval
    • Restoring memory function after brain injury
  • Publications

    • Hippocampal Theta Oscillations Support Successful Associative Memory Formation. Kota S, Rugg MD, Lega BC, The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 12 40 49 9507-9518
    • Direct brain recordings identify hippocampal and cortical networks that distinguish successful versus failed episodic memory retrieval. Tan RJ, Rugg MD, Lega BC, Neuropsychologia 2020 10 147 107595
    • Time cells in the human hippocampus and entorhinal cortex support episodic memory. Umbach G, Kantak P, Jacobs J, Kahana M, Pfeiffer BE, Sperling M, Lega B, Proceedings of the National Academy of Sciences of the United States of America 2020 Oct
    • Commentary: Awake Craniotomy and Memory Induction Through Electrical Stimulation: Why Are Penfield's Findings Not Replicated in the Modern Era? Kulkarni NJ, Lega BC, Neurosurgery 2020 08 87 2 E138-E139
    • Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy. Nair DR, Laxer KD, Weber PB, Murro AM, Park YD, Barkley GL, Smith BJ, Gwinn RP, Doherty MJ, Noe KH, Zimmerman RS, Bergey GK, Anderson WS, Heck C, Liu CY, Lee RW, Sadler T, Duckrow RB, Hirsch LJ, Wharen RE, Tatum W, Srinivasan S, McKhann GM, Agostini MA, Alexopoulos AV, Jobst BC, Roberts DW, Salanova V, Witt TC, Cash SS, Cole AJ, Worrell GA, Lundstrom BN, Edwards JC, Halford JJ, Spencer DC, Ernst L, Skidmore CT, Sperling MR, Miller I, Geller EB, Berg MJ, Fessler AJ, Rutecki P, Goldman AM, Mizrahi EM, Gross RE, Shields DC, Schwartz TH, Labar DR, Fountain NB, Elias WJ, Olejniczak PW, Villemarette-Pittman NR, Eisenschenk S, Roper SN, Boggs JG, Courtney TA, Sun FT, Seale CG, Miller KL, Skarpaas TL, Morrell MJ, Neurology 2020 Jul
    • Functionally distinct high and low theta oscillations in the human hippocampus. Goyal A, Miller J, Qasim SE, Watrous AJ, Zhang H, Stein JM, Inman CS, Gross RE, Willie JT, Lega B, Lin JJ, Sharan A, Wu C, Sperling MR, Sheth SA, McKhann GM, Smith EH, Schevon C, Jacobs J, Nature communications 2020 05 11 1 2469
    • The effects of direct brain stimulation in humans depend on frequency, amplitude, and white-matter proximity. Mohan UR, Watrous AJ, Miller JF, Lega BC, Sperling MR, Worrell GA, Gross RE, Zaghloul KA, Jobst BC, Davis KA, Sheth SA, Stein JM, Das SR, Gorniak R, Wanda PA, Rizzuto DS, Kahana MJ, Jacobs J, Brain stimulation 2020 May
    • Comparison of fMRI correlates of successful episodic memory encoding in temporal lobe epilepsy patients and healthy controls. Hill PF, King DR, Lega BC, Rugg MD, NeuroImage 2020 02 207 116397
    • Longitudinal Differences in Human Hippocampal Connectivity During Episodic Memory Processing. Choi K, Bagen L, Robinson L, Umbach G, Rugg M, Lega B, Cerebral cortex communications 2020 1 1 tgaa010
  • Professional Activities

    • American Association of Neurological Surgeons (2017-2018)
    • Cognitive Neuroscience Society (2012-2018)
    • Congress of Neurological Surgeons (2012-2018)
    • Society for Neuroscience (2011-2018)

Where I Provide Care: