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Dinesh Rakheja, MD $$

Pathologist

Professor Scholar at UT Southwestern Medical Center
Division Director at Children's Health

Languages Spoken:
English

Locations

UT Southwestern Pediatric Group

Biography

Dr. Dinesh Rakheja is the director of Pathology and Laboratory Medicine at Children's Health℠. He is also a Professor of pathology and pediatrics and the chief of Pediatric Pathology at UT Southwestern Medical Center, where he holds the John Lawrence and Patsy Louise Goforth Distinguished Professorship in Pathology. 

Dr. Rakheja earned his medical degree at All India Institute of Medical Sciences in New Delhi. He completed pathology residencies at Maulana Azad Medical College (Delhi University) and UT Southwestern. He trained in gastrointestinal pathology and neuropathology as a senior resident (fellow equivalent) at GB Pant Hospital (Delhi University) and completed a pediatric pathology fellowship at Children’s Health/UT Southwestern.

Dr. Rakheja studies the genetics and metabolism of childhood cancer, particularly Wilms tumor, germ cell tumors, brain tumors, and pediatric sarcomas of bone and soft tissue. He has specific interests in tumor tissue banking, developing primary pediatric cancer cell lines, and developing laboratory assays for diagnostic, prognostic and therapeutic targets in pediatric cancers.

Education and Training

Medical School
All India Institute of Medical Sciences (1992)
Residency
Parkland Health & Hospital System (2003), Pathology
G. B. Pant Hospital (1999), Pathology
Maulana Azad Medical College & Associated Hosps. (1997), Pathology
Fellowship
Parkland Health & Hospital System (2006), Pediatric Pathology
Board Certification
American Board of Pathology/Pediatric Pathology,
American Board of Pathology-Anatomic & Clinical

  • Research Interests

    • Cancer metabolism
    • Neuroblastoma
    • Pediatric brain cancers including Wilms tumor
    • Pediatric genitourinary cancers
    • Pediatric liver cancers
    • Pediatric sarcomas

  • Publications

    Publications

    • Pitfalls in the diagnosis of yolk sac tumor: Lessons from a clinical trial. Yang A, Patterson A, Pavlock T, Chen KS, Gagan J, Hatley ME, Frazier AL, Amatruda JF, Laetsch TW, Rakheja D, Pediatr Blood Cancer 2022 Feb 69 2 e29451
    • MYC, mitochondrial metabolism and O-GlcNAcylation converge to modulate the activity and subcellular localization of DNA and RNA demethylases. Lin AP, Qiu Z, Ethiraj P, Sasi B, Jaafar C, Rakheja D, Aguiar RCT, Leukemia 2022 Jan
    • Acute myeloid leukemia with RAM immunophenotype presenting with extensive mesenteric and retroperitoneal lymphadenopathy: A case report and review of the literature. Wick N, Hitto I, Welder D, Slone T, Koduru P, Fuda F, Rakheja D, Weinberg O, Leuk Res Rep 2022 17 100287
    • Basic Histopathologic Assessment of Germ Cell Tumors for Clinic and Research. Kapur P, Rakheja D, Methods in molecular biology (Clifton, N.J.) 2021 2195 1-11
    • Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney. Brinkley G, Nam H, Shim E, Kirkman R, Kundu A, Karki S, Heidarian Y, Tennessen JM, Liu J, Locasale JW, Guo T, Wei S, Gordetsky J, Johnson-Pais TL, Absher D, Rakheja D, Challa AK, Sudarshan S, Disease models & mechanisms 2020 Sep
    • INTRAUTERINE TRANSMISSION OF SARS-COV-2 INFECTION IN A PRETERM INFANT. Sisman J, Jaleel MA, Moreno W, Rajaram V, Collins RRJ, Savani RC, Rakheja D, Evans AS, The Pediatric infectious disease journal 2020 Jul
    • KANK1-NTRK3 fusions define a subset of BRAF mutation negative renal metanephric adenomas. Catic A, Kurtovic-Kozaric A, Sophian A, Mazur L, Skenderi F, Hes O, Rohan S, Rakheja D, Kogan J, Pins MR, BMC medical genetics 2020 10 21 1 202
    • Disseminated Nannizziopsis Infection in an Adolescent With a STAT1 Mutation. Most ZM, Lieu T, Filkins L, Nicolaides R, Rakheja D, Gelfand A, Kahn J, Open forum infectious diseases 2020 Sep 7 9 ofaa390
    • Neuronal ceroid-lipofuscinoses in Metabolic Diseases: Foundations of Clinical Management, Genetics, and Pathology. 2nd edition. Rakheja D, Bennett MJ (2017), Amsterdam, Netherlands, IOS Press BV
    • Measurement of oncometabolites D-2-hydroxyglutaric acid and L-2-hydroxyglutaric acid in Springer Protocols. Methods in Molecular Biology vol 1633. Acute Myeloid Leukemia: Methods and Protocols. Jones PM, Boriack R, Struys EA, Rakheja D (2017), New York, NY, Humana Press, Springer Nature

    Books

    • Basic histopathologic assessment of germ cell tumors for clinic and research. In Springer Protocols. Methods in Molecular Biology vol 2195. Testicular Germ Cell Tumors. Methods and Protocols. Kapur P, Rakheja D (2021). New York, NY, Humana Press, Springer Nature
    • A Quick Guide to Metabolic Disease Testing Interpretation: Testing for Inborn Errors of Metabolism. Jones P, Patel K, Rakheja D (Ed.) (2020). San Diego, CA, Academic Press, Elsevier

  • Awards and Honors

    • John Lawrence and Patsy Louise Goforth Distinguished Professorship in Pathology (2013)
    • Pediatric Pathology Visiting Scholar, Children’s Hospital Boston, Harvard Medical School (2006)
    • College of American Pathologists Foundation (CAPF) Scholar (2004)
    • Harry B. Neustein Memorial Award, Society for Pediatric Pathology (2004)
    • Travel Award for junior investigators, Society for Inherited Metabolic Disorders (2004)
    • F. Stephen Vogel Award, United States and Canadian Academy of Pathology (2003)
    • Dr. R. P. Mathur Memorial Award in Pathology, Maulana Azad Medical College (Delhi University) (1997)

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