Evaluation of SEDline EEG monitoring in pediatric patients undergoing General Anesthesia or sedation

We intend to collect high resolution eeG data using a SeDLine and o3 modules respectively in pediatric patients and over a wide range of anesthetics, as described in the clinical protocol. in addition, we may collect similar data for inpatient subjects in the newborn intensive Care unit (niCu). For oR subjects, in order to assess the impact of anesthetic drug administration on vital sign parameters routinely used during anesthesia, we intend to collect other noninvasive parametric data including blood pressure, temperature, oxygen saturation and respiratory rate. Blood pressure and temperature will be recorded from the hospital's standard of care devices, while oxygen saturation and respiratory rate will be collected using Masimo Rainbow[RegisteredTM] Pulse Co-oximeter devices. Masimo Rainbow[RegisteredTM] is a noninvasive monitoring platform enabling the assessment of a wide range of blood constituents and physiologic parameters such as total hemoglobin (SpHb), oxygen Saturation (Spo2), Pulse Rate (PR), Perfusion index (Pi). Raw and processed physiological data will be analyzed by Masimo engineering team. Data from this study may be used to create, update and verify that the Patient State index (PSi) algorithm is appropriate for monitoring pediatric patients undergoing anesthesia with a wide variety of anesthetics used in surgical and non-surgical procedures.