Pediatric hypotonia (floppy muscle syndrome)

Hypotonia (hy·​po·​to·​nia) means low muscle tone due to the progressive loss of muscle strength over time.

What is pediatric hypotonia (floppy muscle syndrome)?

Hypotonia, also called floppy muscle syndrome, is a condition that involves the progressive loss of muscle tone over time. Some infants (birth to 1 year) are born with hypotonia, and some children develop hypotonia as a symptom of another condition.

What are the signs and symptoms of pediatric hypotonia (floppy muscle syndrome)?

Symptoms of hypotonia may include:

  • Delayed fine motor skills in children, such as grasping a crayon
  • Delayed gross motor skills in infants, such as holding up head, sitting or crawling
  • Feeding problems, such as trouble sucking or chewing
  • Floppy muscles
  • Frequent hip, jaw and neck dislocation
  • Lack of head control as an infant
  • Shallow breathing
  • Speech delay and speech problems

What are the causes of pediatric hypotonia (floppy muscle syndrome)?

Conditions that may cause hypotonia include:

Brain injury

Cerebral palsy (CP)

Charcot-Marie-Tooth disease

Connective tissue disorders

Down’s syndrome

Ehlers-Danlos syndrome

Encephalitis

Hypothyroidism (congenital)

Marfan syndrome

Meningitis

Muscular dystrophy

Prader-Willi syndrome

Prematurity

Spinal cord injury

Spinal muscular atrophy

Tay-Sachs